The DAC technology in the CJC-1295 enables the compound to bind itself covalently with any
circulating albumin, after it has been administered through a subcutaneous injection. However,
the reason why the half-life could be extended from a few minutes to several days is more
profound. The reactive group in the CJC-1295 binds to a peptide through bioconjugation. The
peptide then finds a neucleophilic unit within the blood and reacts with it in order to create a
When using any GHRH, it should always be remembered that positive results cannot be achieved
overnight. These compounds act steadily over time, and the best results can be achieved slowly,
and with a nutritious diet and a proper exercise regime. Also, these peptides are not sex-
specific, so they do not have any androgenic effects. They can be used by women in the same
dosages that men do.
CJC-1295 DAC has shown some amazing results as a hormone releasing hormone (GHRH)
analog. Not only has CJC-1295 shown the ability to increase hormone and secretion and its
benefits, but it has been able to do so in very large amounts. Recent research studies have
shown that CJC1295 stimulates GH and Secretion, and will keep a steady increase with no
increase in prolactin, leading to intense fat loss, and increases protein synthesis.
CJC-1295 DAC is a long acting Releasing Hormone, which causes the anterior pituitary to
release more hormone. GHRH is released in pulses in the body, which alternate with
corresponding pulses of somatostatin.
The Difference Between CJC-1295 DAC And CJC-1295 NO DAC
1. When a person sees the term CJC 1295 without DAC this is really means that they are looking
at MOD GRF 1-29. This tetrasubstitued peptide is a modified version of the original GRF 1-29
peptide better known as Semorelin.
2. Due to the extreme short half life of the original GRF 1-29, chemists were able to modify the
peptide to offer a longer biological activity that reduced the metabolic clearance. Although with
MOD GRF 1-29 its modification had resulted in a greater peptide bond, the average user will still
likely need to inject two to three times a day with a GHRP to get the maximum effectiveness for
releasing endogenous growth hormone.
3. Now when the drug affinity complex (DAC) was added to CJC 1295, it allowed for an even
greater possibility to utilize smaller GH pulses (what was once thought of as a bleed) that, when
combined with a GHRP, will activate growth hormone stores to release throughout the day and
night. When the DAC component was added, this allowed the peptide half-life to be extended to
about one week and also provided for steadier blood levels after injection. Now that we
understand how important the DAC factor is, this becomes a much more viable and cost effective
way to utilize CJC 1295 with DAC along with a GHRP.
4. The DAC, when added, is able to bind to albumin that circulates the body, literally being able to
last for days as it looks for receptors to bind to. So, in short, if you prefer to use shorter spikes of
GH release then the use of the MOD GRF 1-29 (CJC 1295 without DAC) is going to be optimal.
However, if your prefer fewer injections and still want to unleash your growth hormone stores, then
2-3 times a week injections of CJC 1295 with DAC along with your daily injection of GHRP would
be the way to proceed for maximizing growth hormone release.
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