S4 (Andarine) or Acetamidoxolutamide, is a a selective androgen receptor modulator or SARM for short. It is a research chemical that belongs to SARMS, also called as selective androgen receptor modulators. S4 is said to be the most potent SARM which helps sustain lean muscle mass while stimulating fat loss at the same time. Today, we'll take a closer look on everything there is to know about S4.
Andarine is an orally active partial agonist for androgen receptors. It is less potent in both anabolic and androgenic effects than other SARMs. In an animal model of benign prostatic hypertrophy, andarine was shown to reduce prostate weight with similar efficacy to finasteride, but without producing any reduction in muscle mass or anti-androgenic side effects. This suggests that it is able to competitively block binding of DHT to its receptor targets in the prostate gland, but its partial agonist effects at androgen receptors prevent the side effects associated with the anti-androgenic drugs traditionally used for treatment of BPH.
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