1.How Many Information You Know about GW1516
GW1516, also written GW 50516, is a drug and research chemical developed by pharmaceutical client GlaxoSmithKline, which acts as a PPARδ (peroxisome proliferator activated receptor delta) modulator and selective agonist.GW1516 activates AMP-K (5' adenosine monophosphate-activated protein kinase) and stimulates skeletal muscle glucose uptake.
GW1516 has been demonstrated to effectively reverse metabolic abnormalities in obese men with metabolic syndrome (a pre-diabetic condition), likely due to the fact that it stimulus fatty acid oxidation.
GW1516 holds promise for treating obesity and adiposity and has been touted, much like AICAR, as "exercise in a pill," etc. In conjunction with AICAR, an AMPK agonist which acts synergistically with GW1516, significant increases in exercise endurance have been demonstrated in animal studies.
Through rigorous testing on animal test subjects, scientists have determined that GW1516 has numerous potential health benefits. Because this peptide essentially stimulates the same metabolic pathways as physical exercise and exertion does, the beneficial side effects include increased fat loss and improved endurance. From a purely health perspective, in animal test subjects the administering of GW1516 aided in lowering bad cholesterol, improving good cholesterol, increases insulin sensitivity, and helps reduce the markers for cardiovascular disease.
Benefits of GW1516 Include:
Increased fat loss
Improving good cholesterol
Reducing bad cholesterol
Increasing insulin sensitivity
Reducing markers for cardiovascular disease
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